Myocardial Extracellular Volume Measurement by Cardiac Magnetic Resonance
نویسندگان
چکیده
منابع مشابه
Measurement of extracellular volume fraction by cardiac magnetic resonance imaging detects diffuse myocardial fibrosis in systemic sclerosis
We measured extracellular volume fraction (Ve) from preand post-contrast T1 maps of the left ventricle in 13 patients with systemic sclerosis (SSc) and 13 agematched controls. SSc patients and controls were similar with regard to LV and RV mass, volumes, and function. However, Ve was significantly higher in SSc patients than in controls, even when patients with visible late gadolinium enhanceme...
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OBJECTIVE To measure and assess the significance of myocardial extracellular volume (ECV), determined non-invasively by equilibrium contrast cardiovascular magnetic resonance, as a clinical biomarker in health and a number of cardiac diseases of varying pathophysiology. DESIGN Prospective study. SETTING Tertiary referral cardiology centre in London, UK. PATIENTS 192 patients were mainly r...
متن کاملHistological validation of dynamic-equilibrium cardiovascular magnetic resonance for the measurement of myocardial extracellular volume
Background Extracellular matrix expansion is fundamental to left ventricular (LV) remodeling, and is a therapeutic target. CMR techniques are increasingly used to evaluate myocardial extracellular volume (ECV), however the most widely applied methods are without histological validation. The aim of this study was to provide whole-heart, histological validation of; 1. Dynamic-equilibrium CMR (Dyn...
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BACKGROUND Myocardial extravascular extracellular volume fraction (Ve) measures quantify diffuse fibrosis not readily detectable by conventional late gadolinium (Gd) enhancement (LGE). Ve measurement requires steady state equilibrium between plasma and interstitial Gd contrast. While a constant infusion produces steady state, it is unclear whether a simple bolus can do the same. Given the relat...
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Background Myocardial ECV can be measured using T1 mapping before and after contrast if the contrast agent distribution between blood:myocardial is at equilibrium. Equilibrium distribution can be achieved with a primed contrast infusion (EQ-CMR), or may be approximated by the dynamic equilibration achieved by delayed post bolus measurement. This bolus only approach is highly attractive but curr...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Imaging
سال: 2014
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2013.06.009